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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOLC1
All Species:
42.42
Human Site:
Y682
Identified Species:
71.79
UniProt:
Q14978
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14978
NP_004732.2
699
73603
Y682
T
K
K
K
R
G
S
Y
R
G
G
S
I
S
V
Chimpanzee
Pan troglodytes
XP_001171017
700
73581
Y683
T
K
K
K
R
G
S
Y
R
G
G
S
I
S
V
Rhesus Macaque
Macaca mulatta
XP_001112196
701
73703
Y684
T
K
K
K
R
G
S
Y
R
G
G
S
I
S
V
Dog
Lupus familis
XP_851848
704
74723
Y687
T
K
K
K
R
G
S
Y
R
G
G
S
I
S
V
Cat
Felis silvestris
Mouse
Mus musculus
O08784
1320
134983
K1291
D
K
E
K
K
E
K
K
K
G
K
K
S
L
A
Rat
Rattus norvegicus
P41777
704
73545
Y687
T
K
K
K
R
G
S
Y
R
G
G
S
I
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511079
669
69188
Y629
T
K
K
K
R
G
S
Y
R
G
G
S
I
S
I
Chicken
Gallus gallus
XP_421630
694
72200
Y677
T
K
K
K
R
G
S
Y
C
G
G
T
I
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689627
1001
102013
Y984
T
K
K
K
R
G
S
Y
R
G
G
A
I
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730693
686
70584
K666
F
K
H
E
K
T
K
K
K
R
G
S
Y
R
G
Honey Bee
Apis mellifera
XP_001120943
685
75016
Y669
T
K
K
K
R
G
S
Y
R
G
G
Q
I
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796224
791
84162
Y774
T
K
K
K
R
G
S
Y
R
G
G
Q
I
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001168628
517
55362
Q501
R
G
T
Y
R
G
G
Q
I
D
L
Q
T
H
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32583
406
40997
Y390
N
K
M
K
R
G
S
Y
R
G
G
S
I
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.2
81.5
N.A.
24.9
74.1
N.A.
50.7
43.6
N.A.
36.6
N.A.
27.3
22
N.A.
34.5
Protein Similarity:
100
98.8
95.5
85.6
N.A.
36.7
81.2
N.A.
60.3
57.5
N.A.
47.5
N.A.
42.3
42.9
N.A.
47.9
P-Site Identity:
100
100
100
100
N.A.
20
100
N.A.
93.3
80
N.A.
86.6
N.A.
20
80
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
40
100
N.A.
100
86.6
N.A.
93.3
N.A.
40
80
N.A.
86.6
Percent
Protein Identity:
N.A.
23.6
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
40.9
N.A.
N.A.
39.4
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% D
% Glu:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
86
8
0
0
86
86
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
79
0
8
% I
% Lys:
0
93
72
86
15
0
15
15
15
0
8
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
22
0
0
0
% Q
% Arg:
8
0
0
0
86
0
0
0
72
8
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
79
0
0
0
0
58
8
65
8
% S
% Thr:
72
0
8
0
0
8
0
0
0
0
0
8
8
8
29
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
79
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _